phenolphthalein Report issue

Small molecule Experimental
ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

Oxyphenisatin is a stimulant laxative that has been used by mouth and as an enema. Oxyphenisatin was introduced as Lavema by Winthrop in US in 1959. Oxyphenisatin was used as a cleansing enema apart from x-ray studies and prior to urinary, gastro-intestinal and cholecystography x-ray examination. Oxyphenisatin was also used for preoperative preparation of the large intestine and colon. May be mixed with barium for x-ray examination of the large intestine. Oxyphenisatin may cause jaundice. Oxyphenisatin-induced liver damage usually occurs when the drug has been taken for at least six months and usually two years. Oxyphenisatin was withdrawn in most countries in the early 1970s.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Yes

Alternative names

1,3-dihydro-3,3-bis(4-hydroxyphenyl)-2h-indol-2-one | 3,3-bis(4-hydroxyphenyl)oxindole | 3,3-bis(4-hydroxyphenyl)-oxindole | 3,3-bis(4-hydroxyphenyl)phthalide | 3,3-bis(p-hydroxyphenyl)-2-indolinone | 3,3-bis(p-hydroxyphenyl)oxindole | 4,4'-dihydroxydiphenylisatin | acelax | acetalax | acetophenolisatin | acetphenolisatin | acetphenolisatinum | alophen | bisatin | brocatine | diacetyldihydroxydiphenylisatin | diacetyldioxyphenylisatin | diacetyldiphenolisatin | diasatin | diasatine | dihydroxyphenoloxindol | diphesatin | diphesatine | euchessina | ex-lax | fenolftalein | fenolftaleina | isocrin | lavema | oxifenisatina | oxiphenisatinum | oxyphenisatin | oxyphenisatin acetate | oxyphenisatin diacetate | oxyphenisatine | oxyphenisatine acetate | oxyphenisatinum | phenlaxine | phenlaxinum | phenolisatin | phenolphtaleine | phenolphthalein | phenolphthaleinum | phthalimetten | phthalin | prulet | veripaque | yellow phenolphthalein

Indications (2)

Approved Indications (1)


 

Constipation

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Constipation ()

Gastrointestinal Diseases ()

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