API | nolatrexed

nolatrexed Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Nolatrexed is a thymidylate synthase inhibitor. ^Wikipedia

Chemistry

SMILES: Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccncc1
InChIKey: XHWRWCSCBDLOLM-UHFFFAOYSA-N
Mol. Mass: 284.34
ALogP: 2.36 Partition coefficient
ChEMBL Molecule:
nolatrexed

More Chemistry

Pharmacology

Mechanisms of Action:
- Thymidylate synthase (Homo sapiens) ^UniProt
- Thymidylate synthase (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

3,4-dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)quinazoline dihydrochloride | ag337 | ag 337 | ag-337 | nolatrexed | nolatrexed dihydrochloride | thymitaq

Organizations (1)

Research & Development (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (1)

Liver Neoplasms (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 1
# of Trial Organizations: 1

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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