Active Ingredient History

Dihydroergocristine is an ergot alkaloid that has an partial agonist activity on dopaminergic and alpha-adrenergic receptors and antagonist activity on serotonin receptors. The drug was approved by FDA in combination with other alkaloids (dihydroergocornine, dihydro-alpha-ergocryptine and dihydro-beta-ergocryptine mesylate salts) under the name Hydergine for the treatment of dimentia and cerebrovascular insufficiency.   NCATS

  • SMILES: CC(C)[C@@]1(NC(=O)[C@@H]2C[C@H]3[C@@H](Cc4c[nH]c5cccc3c45)N(C)C2)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C1=O
  • InChIKey: DEQITUUQPICUMR-HJPBWRTMSA-N
  • Mol. Mass: 611.74
  • ALogP: 2.72
  • ChEMBL Molecules:
More Chemistry
9,10-dihydroergocristine | dihydroergocristin | dihydroergocristine | dihydroergocristine mesilate | dihydroergocristine mesylate | gnf-pf-3462

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