API | bi-2536

bi-2536 Report issue

Small molecule Experimental

AACT ChEMBL MeSH PubChem

Active Ingredient History

NOW

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Chemistry

SMILES: CC[C@H]1N(C2CCCC2)c3nc(Nc4ccc(cc4OC)C(=O)NC5CCN(C)CC5)ncc3N(C)C1=O
InChIKey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Mol. Mass: 521.67
ALogP: 3.56 Partition coefficient
ChEMBL Molecule:
bi-2536

More Chemistry

Pharmacology

Mechanism of Action:
- Serine/threonine-protein kinase PLK1 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

bi2536 | bi 2536 | bi-2536

Organizations (4)

Research & Development (4)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (13)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (13)

Breast Neoplasms (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Carcinoma, Small Cell (Phase 2)

Endometrial Neoplasms (Phase 2)

Head and Neck Neoplasms (Phase 2)

Leukemia, Myeloid, Acute (Phase 2)

Lymphoma (Phase 1)

Melanoma (Phase 2)

Neoplasms (Phase 1)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 2)

Prostatic Neoplasms (Phase 2)

Sarcoma (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 11
# of Trial Organizations: 4

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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