Active Ingredient History

NOW
  • Now
Talbutal is a short to intermediate-acting barbiturate, which had been used under brand name Latusate as a sedative and hypnotic, but then this usage was discontinued. It was found, that talbutal binds at a distinct binding site at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. Thus, the post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.   NCATS

  • SMILES: CCC(C)C1(CC=C)C(=O)NC(=O)NC1=O
  • InChIKey: BJVVMKUXKQHWJK-UHFFFAOYSA-N
  • Mol. Mass: 224.2563
  • ALogP: 0.96
  • ChEMBL Molecule:
More Chemistry
5-allyl-5-(1-methylpropyl) barbituric acid | 5-allyl-5-sec-butylbarbituric acid | allyl-sec-butyl-barbituric acid | lotusate | profundol | (rs)-5-allyl-5-sec-butylpyrimidine-2,4,6(1h,3h,5h)-trione | sec-butyl allyl barbituric acid | talbutal | talbutale | talbutalum

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