selenomethionine se-75 Report issue

Small molecule Imaging Approved FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA MeSH PubChem

Active Ingredient History

NOW
  • Now
L-isomer of selenomethionine (Se-met) is a major natural food-form of selenium, synthetic L-Se-met or enriched food sources thereof such as selenium yeast are appropriate supplemental forms of Se for humans; for animals, DL-Se-met is acceptable. Ingested Se-met is either metabolized directly to reactive forms of selenium or stored in place of methionine in body proteins. Se-met metabolism is closely linked to protein turnover. Selenium, which is nutritionally essential for humans, is a constituent of more than two dozen selenoproteins that play critical roles in reproduction, thyroid hormone metabolism, DNA synthesis, and protection from oxidative damage and infection.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Imaging: 75-selenium
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Parenteral
  • Pro Drug: No

Alternative names

75se | l-selenomethionine | radioselenomethionine (75se) | selenomax | selenomethionine | selenomethionine (75se) | selenomethionine (75se) injection | selenomethionine se 75 | selenomethionine se-75 | sethotope | vitaselenium

Organizations (29)

Research & Development (25)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (4)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (14)

Approved Indications (1)


 

Diagnostic Imaging (approved 1973)

Experimental Indications - Clinical Trial Phases 1-4 (13)


 

Carcinoma, Renal Cell (Phase 1/Phase 2)

Carcinoma, Squamous Cell (Phase 2)

Colorectal Neoplasms (Phase 2)

Drug-Related Side Effects and Adverse Reactions (Phase 2)

Irritable Bowel Syndrome (Phase 2)

Lung Neoplasms (Phase 2)

Lymphoma, Follicular (Phase 2)

Mucositis (Phase 2)

Precancerous Conditions (Phase 3)

Prostatic Neoplasms (Phase 3)

Squamous Cell Carcinoma of Head and Neck (Phase 2)

Thyroiditis, Autoimmune (Phase 4)

Xerostomia (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 18
  • # of Trial Organizations: 25

Trials by Phase

Trial Phase Start Date Organizations Indications

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