API | pinacidil

pinacidil (Pindac) Report issue

Small molecule Approved ^FDA

ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW

Pinacidil is a clinically effective vasodilator used for the treatment of hypertension. ^NCATS

Chemistry

SMILES: CC(N/C(=N\C#N)Nc1ccncc1)C(C)(C)C
InChIKey: IVVNZDGDKPTYHK-UHFFFAOYSA-N
Mol. Mass: 245.33
ALogP: 2.35 Partition coefficient
ChEMBL Molecules:

pinacidil

pinacidil

More Chemistry

Pharmacology

Mechanism of Action:
- ATP-binding cassette sub-family C member 9 (Homo sapiens) ^UniProt
- ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Discontinued
Delivery Methods: Oral
Pro Drug: No

Organizations (2)

Research & Development (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (1)

Hypertension (approved 1989)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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