API | pargyline

pargyline (eutonyl) Report issue

Small molecule Approved ^FDA

ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW

Pargyline is an irreversible selective monoamine oxidase (MAO)-B inhibitor, which possesses higher selectivity to this isoform in comparison with MAO-A. It was approved under brand name eutonyl for the treatment hypertension, but then this drug was discontinued. ^NCATS

Chemistry

SMILES: C#CCN(C)Cc1ccccc1
InChIKey: DPWPWRLQFGFJFI-UHFFFAOYSA-N
Mol. Mass: 159.23
ALogP: 1.75 Partition coefficient
ChEMBL Molecules:

pargyline

pargyline hydrochloride

More Chemistry

Pharmacology

Mechanism of Action:
- Amine oxidase [flavin-containing] A (Homo sapiens) ^UniProt
- Amine oxidase [flavin-containing] B (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Discontinued
Delivery Methods: Oral
Pro Drug: No

Combination drugs

eutron ( methyclothiazide (enduron), pargyline (eutonyl) )

Organizations (1)

Research & Development (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (1)

Hypertension

Experimental Indications - Clinical Trial Phases 1-4 (0)

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