oxymetholone (anadrol-50) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Oxymetholone (17beta-hydroxy-2-[hydroxymethylene]-17-methyl-5alpha-androstan-3-one) is a 17alpha-alkylated anabolic-androgenic steroid and a synthetic derivative of testosterone. It has been approved by the US Food and Drug Administration for the treatment of anemias caused by deficient red cell production. Acquired aplastic anemia, congenital aplastic anemia, myelofibrosis and the hypoplastic anemias due to the administration of myelotoxic drugs often respond. Drug interactions exist with cimetidine, paroxetine, and haloperidol, but are not expected with indinavir, ritonavir, clarithromycin, or itraconazole.   NCATS

Chemistry

  • SMILES: C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)\C(C[C@]4(C)[C@H]3CC[C@]12C)=C/O
  • InChIKey: ICMWWNHDUZJFDW-DHODBPELSA-N
  • Mol. Mass: 332.477
  • ALogP: 4.4
  • ChEMBL Molecule:
    oxymetholone  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Alternative names

17β-hydroxy-2-hydroxymethylidene-17α-methyl-3-androstanone | anadrol | anadrol-50 | anapolon 50 | anasteron | anasteronal | ci-406 | hmd | nastenon | oximetholone | oximetolona | oxymethenolone | oxymetholon | oxymetholone | oxymétholone | oxymetholonum | protanabol

Organizations (1)

Research & Development (0)

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Marketing (1)

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Indications (1)

Approved Indications (1)


 

Anemia (approved 1972)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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