oxaprozin (daypro) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Anti-inflammatory effects of Oxaprozin are believed to be due to inhibition of cylooxygenase in platelets which leads to the blockage of prostaglandin synthesis. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Oxaprozin is a non-selective NSAID, with a cell assay system showing lower COX-2 selectivity implying higher COX-1 selectivity. Oxaprozin is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.   NCATS

Chemistry

  • SMILES: OC(=O)CCc1oc(c2ccccc2)c(n1)c3ccccc3
  • InChIKey: OFPXSFXSNFPTHF-UHFFFAOYSA-N
  • Mol. Mass: 293.32
  • ALogP: 4.03
  • ChEMBL Molecules:
    oxaprozin  
    oxaprozin potassium  
More Chemistry

Pharmacology

Drug Pricing (per unit)

United States

$0.3602 - $7.8020
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

4,5-diphenyl-2-oxazolepropionic acid | alvo | apo-oxaprozin | danoprox | daypro | daypro alta | dayrun | deflam | duraprox | oxaprozin | oxaprozina | oxaprozine | oxaprozin potassium | oxaprozinum | rhoxal-oxaprozin | walix | wy 21743 | wy-21743 | wy-21,743

Organizations (16)

Research & Development (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (14)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (4)

Approved Indications (3)


 

Arthritis, Juvenile (approved 1992)

Arthritis, Rheumatoid (approved 1992)

Osteoarthritis (approved 1992)

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Healthy Volunteers (Phase 1)

Overview

  • Highest Phase: Phase 1
  • # of Trials: 1
  • # of Trial Organizations: 2

Trials by Phase

Trial Phase Start Date Organizations Indications

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