mequinol (Solage) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Mequinol (mequinol is 4-hydroxyanisole) is an active ingredient in topical drugs used for skin depigmentation. The mechanism of action of mequinol is unknown. Although mequinol is a substrate for the enzyme tyrosinase and acts as a competitive inhibitor of the formation of melanin precursors, the clinical significance of these findings is unknown.   NCATS

Chemistry

  • SMILES: COC1=CC=C(O)C=C1
  • InChIKey: NWVVVBRKAWDGAB-UHFFFAOYSA-N
  • Mol. Mass: 124.1372
  • ALogP: 3.89
  • ChEMBL Molecules:
    meradimate  
    mequinol  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Missing data
  • Pro Drug: No

Combination drugs

( mequinol (Solage), tretinoin (Retin-A) )

Alternative names

2-aminobenzoate | 4ha | 4-hydroxyanisole | 4-hydroxyanisole, potassium salt | 4-hydroxyanisole, sodium salt | 4-methoxyphenol | bms-181158 | hqmme; hydroxyquinone methyl ether | hydroquinone methyl ether | hydroquinone monomethyl ether | leucobasal | leucodine b | leucodinine b | mechinolum | menthyl anthranilate | mequinol | meradimate | novo-dermoquinona | para-methoxyphenol | p-guaiacol | p-hydroxyanisol | p-hydroxyanisole | p-hydroxymethoxybenzene

Organizations (2)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (1)


 

Pigmentation Disorders (approved 1999)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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