lypressin (diapid) Report issue

Small molecule Approved FDA
ChEMBL Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

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Lypressin is synthetic analog of porcine antidiuretic hormone vasopressin. Itis a cyclic nonapeptide that differs from Arg-vasopressin by one amino acid, containing Lys at residue 8 instead of Arg. Lypressin-containing nasal spray was used to treat diabetes insipidus, but its marketing by Sandoz (Novartis) was discontinued.   NCATS

Chemistry

  • SMILES: NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CSSC[C@H](N)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N2)C(=O)NCC(=O)N
  • InChIKey: BJFIDCADFRDPIO-DZCXQCEKSA-N
  • Mol. Mass: 1056.24
  • ALogP: Missing data
  • ChEMBL Molecule:
    lypressin  
More Chemistry

Pharmacology

Alternative names

diapid | l-8 | lypressin | lysine pitressin | lysine vasopressin | lysipressin | lysopressin | lysylvasopressin | syntopressin

Organizations (2)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (1)


 

Diabetes Insipidus

Experimental Indications - Clinical Trial Phases 1-4 (0)

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