ethinamate (valmid) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Ethinamate was used to treat insomnia (trouble in sleeping) under the brand name VALMID, but then was replaced by other more efficacy medicines. The mechanism of action was not known. However, was studies, which showed that ethinamate inhibits carbonic anhydrases I and did not inhibit II. Nevertheless, even inhibition carbonic anhydrases I is not sufficiently strong to implicate carbonic anhydrases I in the mechanism of action.   NCATS

Chemistry

  • SMILES: NC(=O)OC1(CCCCC1)C#C
  • InChIKey: GXRZIMHKGDIBEW-UHFFFAOYSA-N
  • Mol. Mass: 167.205
  • ALogP: 1.42
  • ChEMBL Molecule:
    ethinamate  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No

Alternative names

1-ethinylcyclohexyl carbamate | 1-ethynylcyclohexanol carbamate | 1-ethynylcyclohexylcarbamate | 1-ethynylcyclohexyl carbamate | aethinyl-cyclohexyl-carbamat | ethinamat | ethinamate | ethinamatum | etinamato | valamid | valamin | valmid | valmidate | volamin

Organizations (1)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (1)


 

Sleep Initiation and Maintenance Disorders

Experimental Indications - Clinical Trial Phases 1-4 (0)

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