estropipate (ogen) Report issue

Small molecule Approved FDA
ChEMBL Drug Central Drugs@FDA MeSH PubChem

Active Ingredient History

NOW
  • Now
Estropipate, also known as piperazine estrone sulfate and sold under the brand names Harmogen, Improvera, Ogen, Ortho-Est, and Sulestrex among others, is an estrogen medication which is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms. It is a salt of estrone sulfate and piperazine, and is transformed into estrone and estradiol in the body. It is taken by mouth.   Wikipedia

Chemistry

  • SMILES: C1CNCCN1.C[C@]12CC[C@@H]3c4ccc(OS(=O)(=O)O)cc4CC[C@H]3[C@@H]1CCC2=O
  • InChIKey: HZEQBCVBILBTEP-ZFINNJDLSA-N
  • Mol. Mass: 436.57
  • ALogP: 3.29
  • ChEMBL Molecule:
    estropipate  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral, Topical
  • Pro Drug: No

Alternative names

estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, compd. with piperazine (1:1) | estropipate | genoral | harmogen | harmonet | ogen | ogen 1.25 | ogen 2.5 | ogen 5 | ogen .625 | ortho-est | piperazine estrone sulfate

Organizations (8)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (8)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (1)


 

Menopause (approved 1977)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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