Active Ingredient History

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Estropipate, also known as piperazine estrone sulfate and sold under the brand names Harmogen, Improvera, Ogen, Ortho-Est, and Sulestrex among others, is an estrogen medication which is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms. It is a salt of estrone sulfate and piperazine, and is transformed into estrone and estradiol in the body. It is taken by mouth.   Wikipedia

  • SMILES: C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(=O)(=O)O)ccc34)[C@@H]1CCC2=O.C5CNCCN5
  • InChIKey: HZEQBCVBILBTEP-ZFINNJDLSA-N
  • Mol. Mass: 436.57
  • ALogP: 3.29
  • ChEMBL Molecule:
More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral, Topical
  • Pro Drug: No
estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, compd. with piperazine (1:1) | estropipate | genoral | harmogen | harmonet | ogen | ogen 1.25 | ogen 2.5 | ogen 5 | ogen .625 | ortho-est | piperazine estrone sulfate

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