cefonicid Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

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Cefonicid is a semi-synthetic broad-spectrum cephalosporin antibiotic resistant to beta-lactamases. Similarly to other cephalosporins, cefonicid exerts its antibacterial activity through the inhibition of the bacterial cell-wall synthesis. Its in vitro and in vivo activity against a wide range of Gram-positive and Gram-negative microorganisms is documented.   NCATS

Chemistry

  • SMILES: O=C(O)C1=C(CSc2nnnn2CS(=O)(=O)O)CS[C@@H]2[C@H](NC(=O)[C@H](O)c3ccccc3)C(=O)N12
  • InChIKey: DYAIAHUQIPBDIP-AXAPSJFSSA-N
  • Mol. Mass: 542.58
  • ALogP: -0.92
  • ChEMBL Molecules:
    cefonicid  
    cefonicid sodium  
More Chemistry

Pharmacology

Alternative names

(6r,7r)-7-{[(2r)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1h-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | cefonicid | cefonicido | cefonicid sodium | cefonicidum | monocid | sk&f-d-75073-z2

Organizations (2)

Research & Development (0)

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Marketing (2)

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Indications (1)

Approved Indications (1)


 

Bacterial Infections (approved 1984)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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