carprofen Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Carprofen is an anti-inflammatory drug developed in Japan by Nippon Roche Research Center. Carprofen, as many NSAIDs, selectively inhibits COX-2 and was shown to suppress inflammation in vitro, using osteoarthritis models. The drug was approved by FDA for human use under the name Ridamyl, however, now it is sold only for veterinary purposes and prescribed for the treatment of postoperative pain and the relief of pain and inflammation associated with osteoarthritis in dogs.   NCATS

Chemistry

  • SMILES: CC(C(O)=O)C1=CC2=C(C=C1)C3=C(N2)C=CC(Cl)=C3
  • InChIKey: PUXBGTOOZJQSKH-UHFFFAOYSA-N
  • Mol. Mass: 273.714
  • ALogP: 4.16
  • ChEMBL Molecule:
    carprofen  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No

Alternative names

(+/-)-2-(3-chloro-9h-carbazol-7-yl)propanoic acid | 2-(6-chloro-9h-carbazol-2-yl)-propionic acid | 6-chloro-alpha-methyl-9h-carbazole-2-acetic acid | (+-)-6-chloro-alpha-methylcarbazole-2-acetic acid | 6-chloro-alpha-methylcarbazole-2-acetic acid | c 5720 | carprodyl | carprofen | carprofène | carprofen, (+-)-isomer | carprofeno | carprofen, (r)-isomer | carprofen, (s)-isomer | carprofenum | (+-)-isomer of carprofen | rimadyl | (r)-isomer of carprofen | ro 205720 | ro 20-5720 | ro-205720 | ro-205720000 | (s)-isomer of carprofen

Organizations (1)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (2)


 

Osteoarthritis (approved 1996)

Pain, Postoperative (approved 1996)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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