API | bethanidine

bethanidine (tenathan) Report issue

Small molecule Approved ^FDA

ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW

Bethanidine is a post-ganglionic adrenergic neurone-blocking agent which exerts a marked postural hypotensive effect. The precise mechanism whereby bethanidine causes blockade of adrenergic neurones is unknown. An initial sympathomimetic effect has been demonstrated in man and animals, possibly due to release of catecholamines. ^NCATS

Chemistry

SMILES: CNC(NC)=NCC1=CC=CC=C1
InChIKey: NIVZHWNOUVJHKV-UHFFFAOYSA-N
Mol. Mass: 177.2462
ALogP: -0.44 Partition coefficient
ChEMBL Molecules:

reproterol

bethanidine

reproterol hydrochloride

bethanidine sulfate

More Chemistry

Pharmacology

Mechanism of Action:
- Sodium-dependent noradrenaline transporter (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Discontinued
Delivery Methods: Missing data
Pro Drug: No

Organizations (1)

Research & Development (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (1)

Hypertension

Experimental Indications - Clinical Trial Phases 1-4 (0)

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