Active Ingredient History
The DPT vaccine or DTP vaccine is a class of combination vaccines against three infectious diseases in humans: diphtheria, pertussis, and tetanus (lockjaw). The vaccine components include diphtheria and tetanus toxoids, and either killed whole cells of the bacterium that causes pertussis or pertussis antigens. The term toxoid refers to vaccines which use an inactivated toxin produced by the pathogen which they are targeted against to generate an immune response. In this way, the toxoid vaccine generates an immune response which is targeted against the toxin which is produced by the pathogen and causes disease, rather than a vaccine which is targeted against the pathogen itself. The whole cells or antigens will be depicted as either "DTwP" or "DTaP", where the lower-case "w" indicates whole-cell inactivated pertussis and the lower-case "a" stands for "acellular". In comparison to alternative vaccine types, such as live attenuated vaccines, the DTP vaccine does not contain any live pathogen, but rather uses inactivated toxoid to generate an immune response; therefore, there is not a risk of use in populations that are immune compromised since there is not any known risk of causing the disease itself. As a result, the DTP vaccine is considered a safe vaccine to use in anyone and it generates a much more targeted immune response specific for the pathogen of interest. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Bacterial Infections and Mycoses (approved 1999)
Alzheimer Disease (Phase 1/Phase 2)
Apnea (Phase 4)
Arthritis, Rheumatoid (Phase 4)
Chickenpox (Phase 3)
Communicable Diseases (Phase 2)
Dengue (Phase 3)
Dengue Virus (Phase 2)
Dermatitis, Atopic (Phase 2)
Diarrhea (Phase 1/Phase 2)
Diphtheria (Phase 4)
Diphtheria-Tetanus-Pertussis Vaccine (Phase 4)
Diphtheria Toxoid (Phase 2)
Dysentery, Bacillary (Phase 1/Phase 2)
Esophageal and Gastric Varices (Phase 2)
Fever (Phase 4)
Haemophilus Infections (Phase 4)
Haemophilus influenzae (Phase 4)
Haemophilus influenzae type b (Phase 4)
Healthy Volunteers (Phase 4)
Hepatitis B (Phase 4)
HIV Infections (Phase 1)
Hospitalization (Phase 4)
Immune System Diseases (Phase 4)
Infant, Premature (Phase 4)
Infant, Premature, Diseases (Phase 4)
Influenza, Human (Phase 4)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 3)
Measles (Phase 3)
Meninges (Phase 2)
Meningitis (Phase 4)
Meningitis, Bacterial (Phase 3)
Meningitis, Meningococcal (Phase 3)
Meningococcal Infections (Phase 4)
Meningococcal Vaccines (Phase 2)
Mortality (Phase 4)
Multiple Sclerosis (Phase 3)
Multiple Sclerosis, Relapsing-Remitting (Phase 3)
Mumps (Phase 3)
Mumps Vaccine (Phase 2)
Neisseria meningitidis (Phase 3)
Neoplasms, Glandular and Epithelial (Phase 3)
Papillomavirus Infections (Phase 4)
Pertussis Vaccine (Phase 4)
Pneumococcal Infections (Phase 2)
Pneumonia, Pneumococcal (Phase 4)
Poliomyelitis (Phase 4)
Poliovirus Vaccines (Phase 2)
Pre-Eclampsia (Phase 4)
Pregnancy (Phase 4)
Pregnancy Complications (Early Phase 1)
Pregnant Women (Phase 2/Phase 3)
Respiratory Tract Infections (Phase 2)
Rotavirus Infections (Phase 4)
Rubella (Phase 3)
Rubella Vaccine (Phase 2)
Seizures, Febrile (Phase 4)
Severe Dengue (Phase 3)
Streptococcal Infections (Phase 2)
Tetanus (Phase 4)
Trismus (Phase 1)
Typhoid Fever (Phase 2)
Uterine Cervical Neoplasms (Phase 4)
Vaccination (Phase 4)
Vaccines (Phase 4)
Whooping Cough (Phase 4)
Yellow Fever (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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