tetranitropentaerythritol Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

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  • Now
Pentaerythritol tetranitrate is an organic nitrate that has been used for the treatment of angina pectoris. Upon administration, the drug undergoes exstensive metabolism to NO which causes vasodilation and the relaxation of smooth muscle cells. The compound belongs to a familiy of explosive substances and may be used accordingly.   NCATS

Chemistry

  • SMILES: [O-][N+](=O)OCC(CO[N+]([O-])=O)(CO[N+]([O-])=O)CO[N+]([O-])=O
  • InChIKey: TZRXHJWUDPFEEY-UHFFFAOYSA-N
  • Mol. Mass: 316.1366
  • ALogP: -1.19
  • ChEMBL Molecule:
    pentaerythritol tetranitrate  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

cardiacap | mycardol | nitropentaerythrite | nitropentaerythritol | pentaerithritol tetranitrate | pentaerithrityl tetranitrate | pentaerythrithyltetrantrate | pentaerythritol tetranitrate | pentanitrine | pentanitrol | pentritol tempules | peritrate | peritrate sa | tetranitropentaerythrite | tetranitropentaerythritol

Organizations (2)

Research & Development (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (1)


 

Angina Pectoris

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Pregnancy, High-Risk (Phase 1/Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 2
  • # of Trial Organizations: 2

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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