lactic acid Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Sodium lactate is primarily indicated as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. Sodium Lactate is most commonly associated with an E number of “E325” Sodium Lactate blends are commonly used in meat and poultry products to extend shelf life and increase food safety. They have a broad antimicrobial action and are effective at inhibiting most spoilage and pathogenic bacteria. In addition sodium lactate is used in cosmetics as a humectant, providing moisture.   NCATS

Chemistry

  • SMILES: CC(O)C(O)=O
  • InChIKey: JVTAAEKCZFNVCJ-UHFFFAOYSA-N
  • Mol. Mass: 90.0779
  • ALogP: -0.55
  • ChEMBL Molecules:
    lactic acid  
    sodium lactate  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No

Combination drugs

( potassium chloride (klor-con), lactic acid, sodium chloride, potassium phosphate (Tis-U-Sol), glucose monohydrate, magnesium )
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( lactic acid, sodium chloride, calcium chloride, glucose monohydrate, magnesium - other names: delflex-lm w/ dextrose, delflex w/ dextrose, delflex w/ dextrose low magnesium, delflex w/ dextrose low magnesium low calcium, dianeal 137 w/ dextrose, dianeal low calcium w/dextrose, dianeal low calcium w/ dextrose, dianeal pd-1 w/ dextrose, inpersol-lc/lm w/ dextrose )
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( lactic acid, sodium chloride, calcium chloride, glucose monohydrate )
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( potassium chloride (klor-con), lactic acid, sodium phosphate, sodium chloride, potassium phosphate (Tis-U-Sol), glucose monohydrate, magnesium )
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( potassium chloride (klor-con), lactic acid, sodium phosphate, potassium phosphate (Tis-U-Sol), glucose monohydrate, magnesium )
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( potassium chloride (klor-con), lactic acid, sodium chloride, calcium chloride )
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( potassium chloride (klor-con), lactic acid, sodium chloride, calcium chloride, glucose monohydrate - other names: dextrose and lactated ringer's, dextrose in half-strength lactated ringer's, dextrose in lactated ringer's, dextrose in modified lactated ringer's, potassium chloride in dextrose and lactated ringer's )
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( lactic acid, citric acid, potassium bitartrate )
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( potassium chloride (klor-con), sodium acetate, lactic acid, sodium chloride, calcium chloride, glucose monohydrate, magnesium )
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( potassium chloride (klor-con), sodium acetate, lactic acid, sodium chloride, calcium chloride, magnesium )
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( potassium chloride (klor-con), lactic acid, sodium bicarbonate, sodium chloride, calcium chloride, glucose monohydrate, magnesium - other names: prismasol b22gk, prismasol bgk )

Alternative names

(±)-2-hydroxypropanoic acid | 2-hydroxypropanoic acid | 2-hydroxypropionic acid | (2rs)-2-hydroxypropanoic acid | acidum lacticum | compound solution of sodium lactate | dl- lactic acid | dl-lactic acid | dl-milchsäure | e270 | e325 | lacolin | lactate | lactic acid | lactic acid, dl- | lactic acid sodium salt | lacticum acidum | l-lactic acid | milchsäure | milk acid | monosodium lactate | rac-lactic acid | sodium lactate | sod lact co | sta363 | α-hydroxypropanoic acid | α-hydroxypropionic acid

Organizations (63)

Research & Development (55)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (9)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (59)

Approved Indications (3)


 

Acid-Base Imbalance

Acidosis (approved 1984)

Electrolytes

Experimental Indications - Clinical Trial Phases 1-4 (56)


 

Acne Vulgaris (Phase 3)

Alcoholic Intoxication (Phase 4)

Behcet Syndrome (Phase 4)

Blood (Phase 2)

Body Fluids (Phase 4)

Brain Diseases (Phase 3)

Brain Injuries (Phase 2)

Brain Injuries, Traumatic (Phase 1/Phase 2)

Breast Neoplasms (Phase 3)

Burns (Phase 4)

Cardiac Output, Low (Phase 3)

Chlamydia (Phase 3)

Contraception (Phase 3)

Coronary Disease (Phase 4)

Craniocerebral Trauma (Phase 2/Phase 3)

Depressive Disorder, Major (Phase 2)

Dermatitis, Atopic (Phase 4)

Diet, Ketogenic (Phase 2)

Drug-Related Side Effects and Adverse Reactions (Phase 3)

Emergencies (Phase 4)

Epilepsy (Phase 2)

Glucose Transporter Type 1 (Phase 2)

Gonorrhea (Phase 3)

Healthy Volunteers (Phase 3)

Heart Arrest (Phase 2)

Heart Failure (Phase 2)

Helicobacter pylori (Phase 4)

Hygiene (Phase 4)

Hyperlactatemia (Early Phase 1)

Hypoglycemia (Phase 4)

Intracranial Hypertension (Phase 3)

Keratosis, Actinic (Phase 2)

Kidney Failure, Chronic (Phase 4)

Liver Transplantation (Phase 4)

Low Back Pain (Phase 1)

Lumbar Vertebrae (Phase 1)

Membranes (Phase 4)

Neoplasms (Phase 3)

Pain (Phase 2)

Peritonitis (Phase 4)

Platelet-Rich Plasma (Phase 3)

Pneumonia (Phase 4)

Psoriasis (Phase 4)

Reperfusion Injury (Phase 2)

Sepsis (Phase 4)

Severe Dengue (Phase 3)

Sexual Dysfunction, Physiological (Phase 3)

Sexually Transmitted Diseases (Phase 3)

Shock, Hemorrhagic (Phase 3)

Shock, Septic (Phase 2/Phase 3)

Sodium Lactate (Phase 3)

Stroke (Phase 2)

Subarachnoid Hemorrhage (Phase 3)

Tonsillitis (Phase 1/Phase 2)

Vaginal Diseases (Phase 2)

Vaginosis, Bacterial (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 106
  • # of Trial Organizations: 55

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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