polihexanide Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Polyhexanide is a polymer used as a disinfectant and antiseptic. In dermatological use, it is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide. PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.   Wikipedia

Chemistry

  • SMILES: CCCCCCNC(=N)NC(=N)N
  • InChIKey: VAZJLPXFVQHDFB-UHFFFAOYSA-N
  • Mol. Mass: 185.27
  • ALogP: 0.57
  • ChEMBL Molecule:
    polihexanide  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

baquacil | cosmocil | lavasept | phmb polymer | polihexanide | polihexanide hydrochloride | polyhexamethylenbiguanid | polyhexamethylenbiguanide | polyhexamethylen-biguanide | poly(hexamethylene biguanide) | polyhexamethylene biguanide | poly(hexamethylenebiguanide) hydrochloride | polyhexamethylene biguanide hydrochloride | polyhexanid | polyhexanide | poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) | poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride | vantocil | vantocil ib of vantocil

Organizations (11)

Research & Development (11)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (10)

Approved Indications (1)


 

Dental Caries

Experimental Indications - Clinical Trial Phases 1-4 (9)


 

Acanthamoeba Keratitis (Phase 1)

Disinfectants ()

Nail Diseases (Phase 4)

Nails, Ingrown (Phase 4)

Neoplasms (Phase 3)

Pressure Ulcer (Phase 3)

Skin Diseases (Phase 4)

Surgical Wound Infection (Phase 3)

Wounds and Injuries (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 8
  • # of Trial Organizations: 11

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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