domperidone Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Domperidone, sold under the brand name Motilium among others, is a dopamine antagonist medication which is used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis. It raises the level of prolactin in the human body and is used off label to induce and promote breast milk production. It may be taken by mouth or rectally.   Wikipedia

Chemistry

  • SMILES: Clc1ccc2N(C3CCN(CCCN4C(=O)Nc5ccccc45)CC3)C(=O)Nc2c1
  • InChIKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N
  • Mol. Mass: 425.92
  • ALogP: 3.35
  • ChEMBL Molecule:
    domperidone  
More Chemistry

Pharmacology

Drug Pricing (per unit)

Australia

$0.0701
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1h-benzo[d]imidazol-2(3h)-one | 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1h-benzo[d]imidazol-2(3h)-one | 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one | domilium | domperidona | domperidone | domperidone betacyclodextrin | domperidone betadex | domperidone maleate | domperidonum | dromperidone | evoxin | motilium | motilium 10 | motilium instants | peridon | r-33812 | vivadone

Organizations (68)

Research & Development (68)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (31)

Approved Indications (1)


 

Motion Sickness

Experimental Indications - Clinical Trial Phases 1-4 (30)


 

Air Travel (Phase 2/Phase 3)

Breast Feeding (Phase 2)

Breast Milk Expression (Phase 2/Phase 3)

Colonoscopy (Phase 4)

Diabetes Mellitus (Phase 4)

Digestive System Diseases ()

Drugs, Investigational (Phase 4)

Dyspepsia (Phase 4)

Edema (Phase 2)

Emotions (Phase 4)

Esophagitis (Phase 3)

Feeding and Eating Disorders (Phase 4)

Gastroenteritis (Phase 3)

Gastroesophageal Reflux (Phase 4)

Gastroparesis (Phase 3)

Healthy Volunteers (Phase 1)

Heartburn (Phase 3)

Heart Diseases (Phase 4)

Hypotension, Orthostatic (Phase 1)

Infant, Premature, Diseases (Phase 2)

Lactation Disorders (Phase 4)

Multiple Sclerosis, Chronic Progressive (Phase 2)

Multiple Sclerosis, Relapsing-Remitting (Phase 2)

Multiple System Atrophy (Phase 1)

Nausea (Phase 3)

Parkinson Disease (Phase 3)

Premature Birth (Phase 4)

Scleroderma, Systemic (Phase 3)

Stomach Diseases (Phase 4)

Vomiting (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 57
  • # of Trial Organizations: 68

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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