varlilumab Report issue

Small molecule Experimental
AACT ChEMBL DrugBank

Active Ingredient History

NOW
  • Now
Varlilumab is a monoclonal antibody designed for immunotherapy for solid tumors and hematologic malignancies. It is an anti-CD27 antibody and helps activate T-cells.   Wikipedia

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

cdx-1127 | varililumab | varilimumab | varlilumab

Organizations (16)

Research & Development (16)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (42)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (42)


 

Astrocytoma (Phase 1)

Bile Duct Neoplasms (Phase 2)

Breast Neoplasms (Phase 1)

Burkitt Lymphoma (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 1/Phase 2)

Carcinoma, Renal Cell (Phase 1/Phase 2)

Cholangiocarcinoma (Phase 2)

Colorectal Neoplasms (Phase 1/Phase 2)

Gallbladder Neoplasms (Phase 2)

Glioblastoma (Phase 2)

Glioma (Phase 1)

Head and Neck Neoplasms (Phase 1/Phase 2)

Hodgkin Disease (Phase 2)

Kidney Diseases (Phase 1/Phase 2)

Kidney Neoplasms (Phase 1/Phase 2)

Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)

Lung Neoplasms (Phase 1)

Lymphoma (Phase 2)

Lymphoma, B-Cell (Phase 2)

Lymphoma, B-Cell, Marginal Zone (Phase 1)

Lymphoma, Large B-Cell, Diffuse (Phase 2)

Lymphoma, Large-Cell, Immunoblastic (Phase 2)

Lymphoma, Mantle-Cell (Phase 1)

Lymphoma, Non-Hodgkin (Phase 2)

Lymphoma, Primary Effusion (Phase 2)

Lymphoma, T-Cell (Phase 2)

Lymphomatoid Granulomatosis (Phase 2)

Melanoma (Phase 2)

Neoplasm Metastasis (Phase 2)

Neoplasms (Phase 1/Phase 2)

Neoplasms by Histologic Type (Phase 1/Phase 2)

Oligodendroglioma (Phase 1)

Ovarian Neoplasms (Phase 1/Phase 2)

Plasmablastic Lymphoma (Phase 2)

Prostatic Neoplasms (Phase 1)

Squamous Cell Carcinoma of Head and Neck (Phase 1/Phase 2)

Triple Negative Breast Neoplasms (Phase 1/Phase 2)

Ulcer (Phase 2)

Urinary Bladder Neoplasms (Phase 1/Phase 2)

Urogenital Neoplasms (Phase 1/Phase 2)

Urologic Diseases (Phase 1/Phase 2)

Urologic Neoplasms (Phase 1/Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 15
  • # of Trial Organizations: 16

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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