s-methionine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
DL-Methionine is a racemic form of the respective sulfur aminoacid. DL-Methionine participates in synthesis of tissue proteins, vitamins, enzymes and hormones taking part in nitrogen, carbohydrate and fat metabolisms, and it is the important source of methyl groups for synthesis of all nucleic acids, as well as the sulfur source for sulfonic compounds. Methionine is used to prevent liver damage in acetaminophen (Tylenol) poisoning. It is also used for increasing the acidity of urine, treating liver disorders, and improving wound healing. Other uses include treating depression, alcoholism, allergies, asthma, copper poisoning, radiation side effects, schizophrenia, drug withdrawal, and Parkinson's disease. It is also used as a food additive in livestock to boost performance. DL-Methionin is the first limiting amino acid in poultry, and probably also in high-yielding cows, and is the second or third limiting amino acid in pigs fed conventional diets.   NCATS

Chemistry

  • SMILES: CSCCC(N)C(O)=O
  • InChIKey: FFEARJCKVFRZRR-UHFFFAOYSA-N
  • Mol. Mass: 149.211
  • ALogP: 0.15
  • ChEMBL Molecule:
    methionine  
More Chemistry

Pharmacology

Alternative names

(2s)-2-amino-4-(methylsulfanyl)butanoic acid | d-methionine | l-a-amino-g-methylthiobutyric acid | l-alpha-amino-gamma-methylmercaptobutyric acid | l-methionin | l-methionine | l-(-)-methionine | l-α-amino-γ-methylmercaptobutyric acid | m | met | methionine | racemethionine | (s)-2-amino-4-(methylthio)butanoic acid | (s)-2-amino-4-(methylthio)butyric acid | (s)-methionine | s-methionine

Organizations (21)

Research & Development (21)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (25)

Approved Indications (1)


 

Urine

Experimental Indications - Clinical Trial Phases 1-4 (24)


 

Acquired Immunodeficiency Syndrome (Phase 3)

Carcinoma, Squamous Cell (Phase 1)

Craniopharyngioma (Phase 2)

Depressive Disorder (Phase 4)

Ependymoma (Phase 2)

Exanthema ()

Glioma (Phase 2)

Head and Neck Neoplasms (Phase 1)

Hearing Loss, Noise-Induced (Phase 3)

Hodgkin Disease (Phase 2)

Hyperparathyroidism, Primary (Phase 2)

Liver Diseases (Phase 4)

Lymphoma, Non-Hodgkin (Phase 2)

Medulloblastoma (Phase 2)

Mucositis (Phase 1)

Neoplasms (Phase 2)

Neuroblastoma (Phase 2)

Osteosarcoma (Phase 2)

Rhabdomyosarcoma (Phase 2)

Sarcoidosis, Pulmonary (Phase 2/Phase 3)

Sarcoma, Ewing (Phase 2)

Spinal Cord Diseases (Phase 3)

Squamous Cell Carcinoma of Head and Neck (Phase 1)

Vitamin B 6 Deficiency (Phase 2/Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 17
  • # of Trial Organizations: 21

Trials by Phase

Trial Phase Start Date Organizations Indications

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