Active Ingredient History
Naproxen (naproxen sodium, NAPROSYN®) is a propionic acid derivative related to the arylacetic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). It is an anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout. The mechanism of action of the naproxen (naproxen sodium, NAPROSYN®), like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Acute Pain (Phase 4)
Alzheimer Disease (Phase 3)
Analgesics (Phase 4)
Analgesics, Opioid (Phase 2)
Anesthesia (Phase 4)
Anterior Cruciate Ligament Injuries (Phase 3)
Anti-Ulcer Agents (Phase 1)
Anxiety Disorders (Phase 4)
Arthritis (Phase 3)
Autoimmune Diseases (Phase 4)
Axial Spondyloarthritis (Phase 3)
Back Injuries (Phase 2)
Back Pain (Phase 4)
Biological Availability (Phase 1)
Breast Neoplasms (Phase 2)
Bunion (Phase 2)
Cardiovascular Diseases (Phase 4)
Cerebrovascular Disorders (Phase 3)
Chronic Pain (Phase 2)
Colorectal Neoplasms (Phase 2)
COVID-19 (Phase 3)
Cytochrome P-450 CYP2C19 (Phase 4)
Dental Implantation, Endosseous (Phase 4)
Drug Interactions (Phase 1)
Drugs, Generic (Phase 1)
Drugs, Investigational (Phase 1)
Dysmenorrhea ()
Dyspepsia (Phase 3)
Elbow (Phase 4)
Fractures, Bone (Phase 4)
General Surgery (Phase 4)
Gout ()
Headache (Phase 3)
Headache Disorders, Primary (Phase 4)
Head and Neck Neoplasms (Phase 2)
Healthy Volunteers (Phase 4)
Hematology (Phase 1)
Hemodynamics (Phase 1)
Hip Fractures (Phase 4)
HIV Infections (Phase 2/Phase 3)
Hypertension (Phase 1)
Hyperuricemia (Phase 1)
Immune Reconstitution Inflammatory Syndrome (Phase 2/Phase 3)
Inflammation (Phase 3)
Intestinal Neoplasms (Phase 1)
Kidney Diseases (Phase 2)
Knee (Phase 3)
Leiomyoma (Phase 4)
Ligaments (Phase 4)
Liver Diseases (Phase 1)
Low Back Pain (Phase 4)
Lyme Disease (Phase 3)
Lymphoma, Large B-Cell, Diffuse (Phase 3)
Menorrhagia (Phase 4)
Migraine without Aura (Phase 3)
Mucositis (Phase 2)
Musculoskeletal Diseases (Phase 3)
Narcotics (Phase 2)
Neoplasms (Phase 3)
Neuralgia (Phase 3)
Obsessive-Compulsive Disorder (Phase 4)
Opioid-Related Disorders (Phase 2)
Ossification, Heterotopic (Phase 4)
Osteoarthritis, Hip (Phase 3)
Osteoarthritis, Knee (Phase 4)
Pain ()
Pain Management (Phase 1/Phase 2)
Pain, Postoperative (Phase 4)
Peptic Ulcer (Phase 4)
Pharmacogenetics (Phase 4)
Pharmacokinetics (Phase 1)
Pharmacology, Clinical (Phase 1)
Pharyngitis (Phase 2)
Platelet Aggregation Inhibitors (Phase 1)
Pleural Effusion (Phase 2)
Pleural Effusion, Malignant (Phase 2)
Post-Traumatic Headache (Phase 4)
Prostatic Neoplasms (Phase 2)
Pulpitis (Phase 2/Phase 3)
Renal Insufficiency (Phase 1)
Sciatica (Phase 4)
Sleep (Phase 4)
Soft Tissue Injuries (Phase 2)
Stomach Diseases (Phase 3)
Stomach Ulcer (Phase 3)
Streptococcus (Phase 4)
Temporomandibular Joint Disorders (Phase 4)
Tennis Elbow (Phase 4)
Tension-Type Headache (Phase 4)
Therapeutic Equivalency (Phase 1)
T-Lymphocytes (Phase 2)
Toes (Phase 2)
Tooth Abnormalities (Phase 4)
Toothache (Phase 3)
Tooth Erosion (Phase 2)
Tuberculosis (Phase 2/Phase 3)
Uterine Diseases (Phase 4)
Vaginal Diseases (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
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