API | tolperisone

tolperisone Report issue

Small molecule Experimental

AACT ChEMBL Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW

Tolperisone is a centrally acting skeletal muscle relaxant used for the treatment of increased muscle tone associated with neurological diseases. It has been used since the 1960s. ^Wikipedia

Chemistry

SMILES: Cc1ccc(C(=O)C(C)CN2CCCCC2)cc1
InChIKey: FSKFPVLPFLJRQB-UHFFFAOYSA-N
Mol. Mass: 245.37
ALogP: 3.3 Partition coefficient
ChEMBL Molecules:

tolperisone

tolperisone hydrochloride

More Chemistry

Pharmacology

Mechanism of Action:
- Sodium channel protein type 2 subunit alpha (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

Organizations (4)

Research & Development (4)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (9)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (9)

Acute Pain (Phase 2)

Back Injuries (Phase 2)

Back Pain (Phase 2)

Healthy Volunteers (Phase 1)

Low Back Pain (Phase 2)

Muscle Cramp (Phase 2)

Muscle Spasticity (Phase 2)

Spasm (Phase 2)

Sprains and Strains (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 6
# of Trial Organizations: 4

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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